Other dosage adjustment recommendations: Also called shingles, zona, and zoster.
The incidence of birth defects in women taking acyclovir is about the same as in the general population. The mean projected daily acyclovir systemic exposures in pediatric subjects across all age-groups 1 to less than 12 years were lower Cmax: For the incidence of laboratory abnormalities see Table 2.
However, spermicidal sperm-killing jelly or a diaphragm will probably not help. The efficacy results are summarized in Table 7. Initiate therapy at first sign or symptom; therapy is most effective if initiated within 48 hours of rash onset. Coadminister IG products at the minimum concentration available and the minimum rate of infusion practicable.
Cancer Support Smartphone Health Apps. WebMD does not provide medical advice, diagnosis or treatment. The risk of adverse effects e. It causes small, painful blisters on your genital area. Valacyclovir is a nucleoside analogue DNA polymerase inhibitor. Type-specific serologic testing of asymptomatic partners of persons with genital herpes can determine whether risk for HSV-2 acquisition exists.
Patients should be advised to initiate treatment at the earliest sign or symptom of chickenpox. Major Consider the risks and benefits of treatment with talimogene laherparepvec before administering acyclovir or other antivirals to prevent or manage herpetic infection. Methods other than breastfeeding should be considered if valacyclovir must be taken while nursing.
Nauseastomach painheadacheor dizziness may occur.
What should I know regarding pregnancy, nursing and administering Valtrex to children or the elderly? No dosage adjustment needed.
This is a decision you and your doctor will make. Viral resistance to acyclovir may occur due to loss of thymidine kinase activity, alterations in thymidine kinase substrate specificity, or decreased DNA-polymerase sensitivity. Acute renal failure and CNS toxicity have been reported in patients with underlying renal dysfunction who have received inappropriately high doses of valacyclovir for their level of renal function.
Cold Sores Nongenital Herpes Simplex Infections Herpes simplex infections are common and when they appear around the mouth and lips, people often refer to them as "cold sores"