Because of their dosage strength, Voltarol prolonged-release tablets mg are not suitable for children and adolescents. Table 1 Blood and lymphatic system disorders.
Mechanism of action Voltarol contains diclofenac sodium, a non-steroidal compound with pronounced antirheumatic, anti-inflammatory, analgesic and antipyretic properties. Treatment should be reviewed at regular intervals and discontinued if no benefit is seen or if intolerance occurs. There have been isolated reports of convulsions which may have been due to concomitant use of quinolones and NSAIDs.
Thrombocytopenia, leucopenia, anemia including haemolytic anemia and aplastic anaemiaagranulocytosis. Except for minimal fetal effects at maternally toxic doses, the prenatal, perinatal and postnatal development of the offspring was not affected. Hypersensitivity, anaphylactic and anaphylactoid reactions including hypotension and shock.
If used concomitantly, diclofenac may raise plasma concentrations of lithium. Diuretics and antihypertensive agents: Patients who experience dizziness, vertigo, somnolence or other central nervous system disturbances, including visual disturbances, while taking NSAIDs should refrain from driving or using machines. Patients should remain alert for the signs and symptoms of serious arteriothrombotic events e. Monitoring of renal function is recommended as a precautionary measure when using Voltarol in such cases.
This is applicable as well for patients who are allergic to other substances, e. Prostaglandins play a major role in causing inflammation, pain, and fever.
Ear and labyrinth disorders.
View all medicines from this company. In particular, it is recommended that the lowest effective dosage be used in frail elderly patients or those with a low body weight.
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Less frequently, gastritis has been observed. In rheumatic diseases, the anti-inflammatory and analgesic properties of Voltarol elicit a clinical response characterised by marked relief from signs and symptoms such as pain at rest, pain on movement, morning stiffness, and swelling of the joints, as well as by an improvement in function. The possibility of prescribing the medicinal product in a single daily dose considerably simplifies long-term treatment and helps to avoid the possibility of dosage errors.
Where the symptoms are most pronounced during the night or in the morning, Voltarol prolonged-release mg should preferably be taken in the evening. Hepatic impairment Diclofenac is contraindicated in patients with severe hepatic impairment see section 4.
Patients with a history of GI toxicity, particularly the elderly, should report any unusual abdominal symptoms especially GI bleeding particularly at the initial stages of treatment. Caution is recommended since concomitant administration could increase the risk of bleeding see section 4.
The patient's need for symptomatic relief and response to therapy should be re-evaluated periodically.