Amitriptyline HCl is 3- 10,dihydro-5 H -dibenzo [ a,d ] cyclohepteneylidene - N,N -dimethylpropanamine hydrochloride. Amitriptyline probably keeps the neurochemicals from being reabsorbed by the releasing cell, allowing them to accumulate in the intercellular space.
To view formulary information first create a list of plans. Deaths may occur from overdosage with this class of drugs.
The usual maintenance dosage of amitriptyline HCl is 50 to mg per day. This drug is available at a higher level co-pay. Quantity Limits Drugs that have quantity limits associated with each prescription. Increases in plasma levels of tricyclic antidepressants, and in the frequency and severity of side effects, particularly anticholinergic, have been reported when cimetidine was added to the drug regimen.
Safety and efficacy have not been established in patients younger than 12 years. Tricyclic antidepressants possess affinity for muscarinic and histamine H1 receptors to varying degrees.
Dosing & Uses
Close supervision is required when amitriptyline is given to hyperthyroid patients or those receiving thyroid medication. Disturbance in attention, dysgeusia. Following gastric lavage, activated charcoal may be administered.
This restriction requires that specific clinical criteria be met prior to the approval of the prescription. Amitriptyline can make you sunburn more easily.
A sedative effect may be apparent before the antidepressant effect is noted, but an adequate therapeutic effect may take as long as 30 days to develop. This drug is not recommended for use during the acute recovery phase following myocardial infarction. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records.
An ECG should be taken and close monitoring of cardiac function instituted if there is any sign of abnormality. Uncommon Diarrhoea, vomiting, tongue oedema. Amitriptyline and the main metabolite nortriptyline pass across the placental barrier. In some patients 40 mg per day is sufficient.
If consciousness is impaired, the airway should be secured prior to lavage. Paralytic ileus; hyperpyrexia; urinary retention; dilatation of the urinary tract; constipation; blurred vision, disturbance of accommodation, increased ocular pressure, mydriasis; dry mouth.
Nocturnal enuresis Paediatric population The recommended doses for: This should include, large volume gastric lavage followed by activated charcoal. The dose can be taken once daily, or be divided into two doses. Common Disturbance in attention, dysgeusia.