Colchicine inhibits microtubule

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Tetrahedron 72 With this monopoly pricing power, the price of colchicine increased. This paragraph needs additional citations for verification. C Risk not ruled out. Mechanism of Action of Colchicine in the Treatment of Gout.

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Biochemistry 0 proofing. How to cite this comment: One of the important functions of microtubules is to move and separate chromosomes and other components of the cell for cell division mitosis. Cell Structure and Function 24 5 Biochemistry 38 6 Colchicine is a medication most commonly used to treat gout. The results indicate that inhibition of tubulin incorporation at microtubule ends is caused by colchicine-liganded tubulin in the form of a final-state complex.

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This experiment is crucial to many forms of cancer research. In certain species, colchicine-induced triploidy has been used to create "seedless" fruit, such as seedless watermelons Citrullus lanatus. PandeyManoj KumarOm P. MierkeJosef A. Adding colchicine to a culture during mitosis is part of the standard procedure for doing karyotype studies. Microtubules are involved in vesicular transport.

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Activation by Microtubule-Promoting Cosolvents. These metrics are regularly updated to reflect usage leading up to the last few days. February 3, "Letters to Editor: Wheat is typically tetraploid and rye diploid, with their triploid hybrid infertile; treatment of triploid triticale with colchicine gives fertile hexaploid triticale.

Biochemical Pharmacology 78 9 A fluorescence stopped flow study of colchicine binding to tubulin. Soft Matter 7 24 Microtubules are long polymers made of smaller units monomers of the protein tubulin. Symptoms of toxicity include gastrointestinal upset, fever, muscle painlow blood cell countsand organ failure.