Methotrexate does block folate, but the way it treats RA seems to be mostly unrelated to blocking folate. If your doctor prescribes methotrexate for your RA, talk to them about your risk of folate deficiency and the possibility of using folic acid to prevent side effects.
Evidence type Guidance and Policy Source American College of Gastroenterology 2. When taking bile acid sequestrants for cholesterol, you should take folate at a different time of day. Every effort has been made to ensure that the information provided by Multum is accurate, up-to-date and complete, but no guarantee is made to that effect.
Methotrexate's interference with healthy cells can lead to side effects, such as mouth soreness, a low white blood cell count, hair loss and birth defects.
Featured Centers Feeling Short of Breath? These side effects can often be short-circuited by taking a folic acid supplement. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.
Thank you for sharing your feedback. Cochrane Database of Systematic Reviews - 31 May In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof.
Folic Acid for Rheumatoid Arthritis. Reasons for Blood Cancer. However, it can decrease the levels of an important vitamin in your body called folate. All generic drug interactions for methotrexate sodium oral lists will include brand and generic names:. Talk to your doctor first.
Folic Acid Is a Must
The Effects of Chemotherapy on Teeth. Minor Interaction is unlikely, minor, or nonsignificant. Herbal Cancer Treatments for Lymphoma. Multum's information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill, knowledge, and judgement of healthcare practitioners in patient care. When you use methotrexate to treat RA, it helps decrease pain and swelling by blocking certain chemicals in your body that lead to inflammation.
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