Phenytoin Dilantin is an anti-epileptic medication that works by slowing down the impulses in the brain that cause seizures. If this drug is used during pregnancy, or if the patient becomes pregnant while taking the drug, the patient should be apprised of the potential harm to the fetus.
Patients stabilized on a daily oral regimen of Dilantin experience a drop in peak blood levels to percent of stable levels if crossed over to an equal dose administered intramuscularly.
Continuous monitoring of the electrocardiogram and blood pressure is essential. The serum concentration of Phenytoin can be decreased when it is combined with Levomefolic acid. Phenytoin may cause swelling and bleeding of the gums. Examples include amiodaroneazole antifungals such as itraconazolemacrolide antibiotics such as erythromycinestrogensisoniazidrifamycins such as rifabutinSt.
Some recommend avoiding polytherapy and maintaining the minimal dose possible during pregnancy, but acknowledge that current data do not provide clear answers.
What is phenytoin?
Because it takes time for the bound drug to dissociate from the inactive channel, there is a time dependent block of the channel. Otherwise, call a poison control center right away. Fragile X Syndrome Fragile X syndrome is the most common inherited form of mental retardation.
Phenytoin may increase the central nervous system depressant CNS depressant activities of Thalidomide. Another precaution with phenytoin treatment is the risk for osteomalacia softening of the bonesthought to be caused by phenytoin's interference with vitamin D metabolism.
Add to Cabinet Add Adderall to my medicine cabinet. Schizophrenia and Mental Health. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient.
The risk or severity of adverse effects can be increased when Glutethimide is combined with Phenytoin. Dilantin should be discontinued at the first sign of a rash, unless the rash is clearly not drugrelated.
The serum concentration of Phenytoin can be decreased when it is combined with 2,5-Dimethoxyethylamphetamine. Risks involved outweigh potential benefits.
It is important to be aware of the signs and symptoms of serious skin reactions so you can recognize them if they occur. Blockers Glibenclamide Lonidamine Piretanide. The risk or severity of adverse effects can be increased when Phenytoin is combined with Alaproclate.
Managing Type 1 Diabetes. The risk or severity of adverse effects can be increased when Deramciclane is combined with Phenytoin. Consider using other options if possible.